. Tapentadol is an effective medication for the treatment of both acute as well as chronic pain, and it has a dual mechanism of action. Headaches are severe throbbing pain, and they can cause nausea, vomiting, and many others. The mechanism of tapentadol is that it helps in blocking the pain sensation from travelling to the brain receptors, which helps in reducing the pain. It is a medication that helps to get better from the pain sensation within 30 minutes of its intake. There are certain side effects of tapentadol. For more information about the side effects and precautions, click here.