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Indicated for: Epilepsy (Lennox-Gastaut Syndrome, Akinetic Seizures, Myoclonic Seizures, Absence Seizures, Generalized Tonic-Clonic Seizures, Focal Seizures, Infantile Spasms), Panic Disorder with or without Agoraphobia, Agoraphobia, Paroxysmal Anxiety, Acute Mania (Adjunctive Therapy), Restless Legs Syndrome, REM Sleep Behavior Disorder, Essential Tremor, Acute Alcohol Withdrawal Syndrome.
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The relief provided is both physiological and psychological as the constant twitching can be a source of significant social anxiety and self-consciousness. The importance of treating REM Sleep Behavior Disorder extends far beyond the immediate goal of preventing sleep related injuries and improving the quality of sleep for the patient and their bed partner. By enhancing GABAergic transmission within the pontine tegmentum and the descending inhibitory pathways that project to the spinal alpha motor neurons, Clonazepam effectively reinstates the muscular paralysis that is the hallmark of normal REM sleep, thereby confining the action of the dream to the realm of the mind and preventing its physical enactment in the real world. Aurobindo Clonazepam. In Canada healthcare providers and patients alike appreciate the availability of medications that can target these specific movement disorders without causing excessive sedation when titrated properly.
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