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Indicated for: Epilepsy (Lennox-Gastaut Syndrome, Akinetic Seizures, Myoclonic Seizures, Absence Seizures, Generalized Tonic-Clonic Seizures, Focal Seizures, Infantile Spasms), Panic Disorder with or without Agoraphobia, Agoraphobia, Paroxysmal Anxiety, Acute Mania (Adjunctive Therapy), Restless Legs Syndrome, REM Sleep Behavior Disorder, Essential Tremor, Acute Alcohol Withdrawal Syndrome.
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This is why the rapid and effective management of the acute phase is so critically important not only for the immediate safety of the patient but also for minimizing the potential long term consequences of the manic behavior. Benadryl has absolutely no role in the management of REM Sleep Behavior Disorder, and its use in this context would be both ineffective and potentially harmful, as its anticholinergic properties could exacerbate cognitive impairment in what is often an older adult population at risk for neurodegenerative disease, and its nonspecific sedative effects would do nothing to restore the deficient brainstem-mediated motor inhibition. The patient's safety, and the safety of those around them, depends upon their absolute and unwavering adherence to the prohibition against combining these two powerful central nervous system depressants. Pills Keep You Awake. The anxiety disorder, if it is of sufficient severity and has not responded to adequate trials of first-line serotonergic antidepressants or evidence-based psychotherapy such as cognitive behavioral therapy, may require its own targeted pharmacotherapy.
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